Publications

Pivotal Study

• Sen-Gupta, E., Wright, D.E., Caccese, J.W., Wright Jr., J.A., Jortberg, E., Bhatkar, V., Ceruolo, M., Ghaffari, R., Clason, D.L., Maynard, J.P., Combs, A.H. (2019) "A Pivotal Study to Validate the Performance of a Novel Wearable Sensor and System for Biometric Monitoring in Clinical and Remote Environments," Digital Biomarkers 3:1-13
   

UCB Collaboration

• Boroojerdi, B., Claes, K., Ghaffari, R., Mahadevan, N., Markowitz, M., Melton, K., Morey, B., Otoul, C., Patel, S., Phillips, J., Sen-Gupta, E., Stumpp, O., Tatla, D., Wright, J. A., Sheth, N. (2017) "Clinical Feasibility of a Wearable, Conformable Sensor Patch to Monitor Motor Symptoms in Parkinson’s Disease," 21st International Congress of Parkinson's Disease and Movement Disorders 

• Boroojerdi, B., Claes, K., Ghaffari, R., Mahadevan, N., Markowitz, M., Melton, K., Morey, B., Otoul, C., Patel, S., Phillips, J., Sen-Gupta, E., Stumpp, O., Tatla, D., Wright, J. A., Sheth, N. (2017) "Clinical Feasibility of a Wearable, Conformable Sensor Patch to Monitor Motor Symptoms in Parkinson’s Disease," 21st International Congress of Parkinson's Disease and Movement Disorders (Poster)

Movement Phenotyping

Motor Symptoms / Parkinson's / Huntington's

• Jamie L. Adamsa, Karthik Dinesh, Mulin Xiong, Christopher G. Tarolli, Saloni Sharma, Nirav Sheth, A.J. Aranyosi, William Zhu, Steven Goldenthal, Kevin M. Biglan, E. Ray Dorsey, Gaurav Sharma, (2017) "Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home," Digital Biomarkers 1:52-63

• Sharma, G., "'Digital Biomarkers' for Huntington's Disease using Multible Body-affixed, Light-weight Sensors," University of Rochester

• K. Dinesh, M. Xiong, J. Adams, R. Dorsey, and G. Sharma, “Signal analysis for detecting motor symptoms in parkinson's and huntington's disease using multiple body-affixed sensors: A pilot study,” in Proc. IEEE Western NY Image and Signal Proc. Workshop (WNYISPW) , Nov. 2016.

• Boroojerdi, B., Ghaffari, R., Mahadevan, N., Markowitz, M., Melton, K., Morey, B., Otoul, C., Patel, S., Phillips, J., Sen-Gupta, E., Stumpp, O., Tatla, D., Terricabras, D., Claes, K., Wright Jr, J. A., Sheth, N. (2018) "Clinical Feasibility of a Wearable, Conformable Sensor Patch to Monitor Motor Symptoms in Parkinson’s Disease," Parkinsonism & Related Disorders.

• Jortberg, E., Silva, I., Bhatkar, V., McGinnis, R. S., Sen-Gupta, E., Morey, B., Wright Jr, J. A., Pindado, J., Bianchi, M. T. (2018) “A Novel Adhesive Biosensor System for Detecting Respiration, Cardiac, and Limb Movement Signals During Sleep: Validation with Polysomnography,” Nature and Science of Sleep.

• Sun, R., Moon, Y., McGinnis, R., Seagers, K., Motl, R. W., Sheth, N., Wright, J. A., Ghaffari, R., Sosnoff, J. J.(2017) Assessment of Postural Sway in Individuals with Multiple Sclerosis Using a Novel Wearable Inertial Sensor. Digit Biomark 2018;2:1-10

• Moon, Y., McGinnis, R., Seagers, K., Motl, R. W., Sheth, N., Wright, J. A., Ghaffari, R., Sosnoff, J. J.(2017) Monitoring gait in multiple sclerosis with novel wearable motion sensors. PLoS ONE 12(2): e0171346. doi:10.1371/journal.pone.0171346 (Paper)

• McGinnis, R., Mahadevan, N., Moon, Y., Seagers, K., Sheth, N., et al. (2017) A machine learning approach for gait speed estimation using skin-mounted wearable sensors: From healthy controls to individuals with multiple sclerosis. PLOS ONE 12(6): e0178366.

• Sun, R., Moon, Y., McGinnis, R., Seagers, K., Motl, R. W., Seth, N., Wright, J. A., Ghaffari, R., Sosnoff, J. J. (2017) A Soft, Flexible Skin-Mounted Sensor for Monitoring Balance Deficits in People with Multiple Sclerosis. The Consortium of Multiple Sclerosis Centers Annual Meeting. (Poster)

Cardiac

• Kabir, M. M., Perez-Alday, E., Thomas, J., Sedaghat, G., Tereshchenko, L. (2016) Optimal configuration of adhesive ECG patches suitable for long-term monitoring of a vectorcardiogram Journal of Electrocardiology:10.1016/j.jelectrocard.2016.12.005

Range of Motion

• McGinnis, R., Patel S., Silvaro, I., Mahadevan, N., DiCristofaro, S., Jortberg, E., Ceruolo, M., and Aranyosi, A. J. (2016) Skin Mounted Accelerometer System for Measuring Knee Range of Motion. IEEE EMBC (Poster)

Data Science and Machine Learning

• McGinnis, R., Mahadevan, N., Moon, Y., Seagers, K., Sheth, N., et al. (2017) A machine learning approach for gait speed estimation using skin-mounted wearable sensors: From healthy controls to individuals with multiple sclerosis. PLOS ONE 12(6): e0178366.

• Patel, S., McGinnis, R., Silva, I., DiCristofaro, S., Mahadevan, N., Jortberg, E., Franco, J., Martin, A., Lust, J., Raj, M., McGrane, B., Petrillo, P., Aranyosi, A. J., Ceruolo, M., Pindado, J., Ghaffari, R. (2016) A Wearable Computing Platform for Developing Cloud-based Machine Learning Models for Health Monitoring Applications. IEEE EMBC.

• A. Nadeau, K. D. Dinesh, G. Sharma, and M. Xiong, “In-situ calibration of accelerometers in body-worn sensors using quiescent gravity,” in Proc. IEEE Intl. Conf. Acoustics Speech and Sig. Proc. , New Orleans, USA, March 2017, p. 2192-2196.

• Lonini, L., Dai, A., Shawen, N., Simuni, T., Poon, C., Shimanovich, L., Daeschler, M., Ghaffari, R., Rogers, J. A., Jayaraman, A. (2018) “Wearable Sensors for Parkinson’s Disease: Which Data Are Worth Collecting for Training Symptom Detection Models,” Digital Medicine.

*The BioStampRC system is designed to collect certain physiological data in research studies. The system is intended to capture raw data about movements and biopotentials. The data collected by the BioStampRC system can provide quantifiable analysis of physical motion and electrophysiology. BioStampRC Sensors are research tools and are not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of any disease or condition in humans or animals.

• Hsu, Y.-Y., Lucas, K., Davis, D., Elolampi, B., Ghaffari, R., Rafferty, C. and Dowling, K. (2013) A novel strain relief design for multilayer thin film stretchable interconnects. IEEE Trans. Electron Devices. 60:2338-2345.
• Hsu, Y.-Y., Lucas, K., Davis, D., Ghaffari, R., Elolampi, B., Dalal, M., Work, J., Lee, S., Rafferty, C. and Dowling, K. (2013) Design for reliability of multilayer thin film stretchable interconnects. IEEE Electronic Components & Technology Conf. 623-628.
• Ghaffari, R., Schlatka, B., Balooch, G., Huang, Y. and Rogers, J. A. (2013) Reinventing biointegrated devices. Materials Today 16:156-157.
• Song, D., Lee, J., Qiao, S., Ghaffari, R. et al. (2014) Multifunctional wearable devices for diagnosis and treatment of movement disorders. Nature Nanotechnology 9:397-404.
• Wei, P., Raj, M… and Ghaffari, R. (2014) A stretchable and flexible system for skin-mounted measurement of motion tracking and physiological signals. IEEE EMBC.
• Hsu, Y.-Y., Papkyrikos, C., Liu, D., Wang, X., Raj, M., Zhang, B. and Ghaffari, R. (2014). Design for reliability of multi-layer stretchable interconnects. J. Micromechanics and Microengineering. 24:95014-95020
• Kim, J… Ghaffari, R., Huang, Y., Gupta, S., Paik, U. and Rogers, J.A. (2015) Epidermal electronics with advanced capabilities in near field communication. Small.doi: 10.1002/smll.201402495.
• Choi, S., Lee, H., Ghaffari, R., Hyeon, T. and Kim, D. H. (2016) Recent advances in flexible and stretchable bioelectronics devices integrated with nanomaterials. Adv Materials. doi: 10.1002/adma.201504150.
• Rogers, J. A., Ghaffari, R. and Kim, D. H. (2016) Stretchable Bioelectronics for Medical Devices and Systems. Springer Publisher. ISBN 978-3-319-28694-5
• Raj, M.,… and Ghaffari, R. (2016) Multifunctional epidermal sensor systems with ultrathin encapsulation packaging for health monitoring. In Book: Stretchable Bioelectronics for Medical Devices and Systems.  Springer Publisher. ISBN 978-3-319-28694-5.

• Kim, D.-H., Lu, N., Ghaffari, R. et al. (2011) Multifunctional stretchable devices on compliant balloon catheters for in-vivo electrophysiological mapping and ablation therapy. Nature Materials 10(4), 316-323. PMID: 21378969
• Kim, R.-H., Kim, D.-H., Xiao, J., Kim, B.-H., Park, S.-I., Panilaitis, B., Ghaffari, R., et al (2010) Waterproof AlInGaP optoelectronics on flexible tubing, sutures, gloves, and other unusual substrates, with applications examples in biomedicine and robotics. Nature Materials 9(11): 929-37. PMID: 20953185
• Slepian, M., Ghaffari, R. and Rogers, J. A. (2011) Multifunctional balloon catheters of the future. Interventional Cardiology 3(4), 417-419.
• Kim, D.-H., Lu, N., Ghaffari, R. and Rogers, J. A. (2012) Inorganic semiconductor nanomaterials for flexible and stretchable biointegrated devices. NPG Asia Materials 4, e15, doi: 10.1038/am.2012.27.
• Kim, D.-H., Ghaffari, R., Lu, N. and Rogers, J. A. (2012) Flexible and stretchable electronics for biointegrated devices. Annu. Rev. Biomed. Eng. 14:113-1128.
• Kim, D.-H., Wang, S., Keum, H., Ghaffari, R., et al. (2012) Thin, flexible sensors and actuators integrated in surgical sutures for targeted wound monitoring and therapy. Smalldoi: 10.1002/smll.201200933.
• Kim, D.-H., Ghaffari, R. et al (2012) Electronic sensor and actuator webs for large-area complex geometry cardiac mapping and therapy. Proc. Natl. Acad. Sci. USA. 109:19910-19915.
• Chung, H.-J., Sulkin, M. S., Kim, J.-S., Goudeseune, C., Chao, H.-Y, Song, J.-W., Yang, S.-Y., Hsu, Y.-Y., Ghaffari, R., Efimov, I. R. and Rogers, J. A. (2013) Ultrathin, stretchable, multiplexing pH sensor arrays on biomedical devices with demonstrations on rabbit and human hearts undergoing ischemia. Advanced Healthcare Materials DOI: 10.1002/adhm.201300124.
• Su, Y., Liu, Z., Ghaffari, R., Wang, S., Hwang, K.C., Rogers, J. A. and Huang, Y. (2014) Mechanics of stretchable electronics on balloon catheter under extreme deformation. International Journal of Solids and Structures. 51: 1555-1561.
• Dagdeviren, C., … Ghaffari, R., Huang, Y., Slepian, M. J. and Rogers, J. A. (2014) Conformal, multilayer piezoelectric energy harvesting and storage from motions of the heart, lung and diaphragm. Proc. Natl. Acad. Sci. USA. 111:1927-1932.
• Kim, J., Lee, M., Shim, H. J., Ghaffari, R. et al. (2014) Stretchable silicon nanoribbon electronics for skin prosthesis. Nature Communications. doi: 10.1038/ncomms6747
• Son, D., Lee, J., Lee, D. J., Ghaffari, R., et al. (2015) Bioresorbable electronic stent integrated with therapeutic nanoparticles for endovascular diseases. ACS Nano.
• Swanson, C. D., Lee, S., Aranyosi, A. J., Tien, B., Chan, C., Wong, M., Lowe, J., Jain, S. and Ghaffari, R. (2015) Rapid light transmittance measurements in paper-based microfluidic devices. Sensing and Biosensing Research. 5:55-61.
• Dagdeviren, C., Shi, Y., Joe, P. Ghaffari, R., et al. (2015) Conformal piezoelectric systems for clinical and experimental characterization of soft tissue biomechanics. Nature Materials. DOI: 10.1038/nmat4289.
• Choi, M.K., Park, O.K., Choi, C., Qiao, S., Ghaffari, R., et al. (2015) Cephalopod-Inspired Miniaturized Suction Cups for Smart Medical Skin. Advanced Healthcare Materials. DOI: 10.1002/adhm.201500285.
• Lee, S., Klinker, L… and Ghaffari, R. (2015) Catheter-Based Systems With Integrated Stretchable Sensors and Conductors in Cardiac Electrophysiology. Proceedings of the IEEE. 103:682-689.
• Klinker, L., Lee, S… and Ghaffari, R. (2015) Balloon catheters with integrated stretchable electronics for electrical stimulation, ablation and blood flow monitoring. Extreme Mechanics Letters. 3:45-54.
• Lee, H., Lee, Y., Song, C., Cho, H. R., Ghaffari, R. et al. (2015) An endoscope with integrated transparent bioelectronics and theranostic nanoparticles for colon cancer treatment. Nature Communications. 6:10059.
• Lee, S., … Ghaffari, R., and Swanson, C. D. (2016) Flexible opto-electronics enabled microfluidics systems with cloud connectivity for point-of-care micronutrient analysis. Biosens. Bioelectron. 78:290-299.
• Lee, H., Choi, T. K., Lee, Y. B., Cho, R., Ghaffari, R. et al. (2016) A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy. Nature Nanotechnology doi: 10.1038/nnano.2016.38.